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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Del(2Hoxd8-Hoxd13)11Ddu
deletion, Chr 2, Denis Duboule 11
MGI:3616177
Summary 13 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Del(2Hoxd8-Hoxd13)11Ddu/Del(2Hoxd8-Hoxd13)11Ddu involves: 129S2/SvPas MGI:5305757
cn2
 		Del(2Hoxd8-Hoxd13)11Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Hoxatm1Ddu/Del(6Hoxa)1Ddu
Tg(Prrx1-cre)1Cjt/0 		involves: 129S2/SvPas * C57BL/6J * SJL/J MGI:3715861
cx3
 		Dp(2Evx2-Atf2)59Ddu/Del(2Hoxd8-Hoxd13)11Ddu involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas MGI:5469822
cx4
 		Dp(2Lnp-Atf2)60Ddu/Del(2Hoxd8-Hoxd13)11Ddu involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas MGI:5469823
cx5
 		Dp(2Evx2)61Ddu/Del(2Hoxd8-Hoxd13)11Ddu involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas MGI:5469824
cx6
 		Del(2Atf2)50Ddu/Del(2Hoxd8-Hoxd13)11Ddu involves: 129P2/OlaHsd * 129S2/SvPas MGI:5469826
cx7
 		Dp(2Lnp)62Ddu/Del(2Hoxd8-Hoxd13)11Ddu involves: 129S1/Sv * 129S2/SvPas MGI:5469825
cx8
 		Del(2Lnp)48Ddu/Del(2Hoxd8-Hoxd13)11Ddu involves: 129S2/SvPas * C57BL/6 * SJL MGI:5305758
cx9
 		Del(2)49Ddu/Del(2Hoxd8-Hoxd13)11Ddu involves: 129S2/SvPas * C57BL/6 * SJL MGI:5305759
cx10
 		Del(2Evx2)51Ddu/Del(2Hoxd8-Hoxd13)11Ddu involves: 129S2/SvPas * C57BL/6 * SJL MGI:5305760
cx11
 		Del(2Atf2)52Ddu/Del(2Hoxd8-Hoxd13)11Ddu involves: 129S2/SvPas * C57BL/6 * SJL MGI:5305762
cx12
 		Del(2Evx2-Atf2)53Ddu/Del(2Hoxd8-Hoxd13)11Ddu involves: 129S2/SvPas * C57BL/6 * SJL MGI:5305764
cx13
 		Del(2Atf2)50Ddu/Del(2Hoxd8-Hoxd13)11Ddu involves: 129S2/SvPas * C57BL/6 * SJL MGI:5305767


Genotype
MGI:5305757
hm1
Allelic
Composition		 Del(2Hoxd8-Hoxd13)11Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic
Background		 involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal phalanx morphology ( J:178930 )
• missing or fused phalanges at birth
brachydactyly ( J:178930 )
• at birth

skeleton
abnormal phalanx morphology ( J:178930 )
• missing or fused phalanges at birth




Genotype
MGI:3715861
cn2
Allelic
Composition		 Del(2Hoxd8-Hoxd13)11Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Hoxatm1Ddu/Del(6Hoxa)1Ddu
Tg(Prrx1-cre)1Cjt/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6J * SJL/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(2Hoxd8-Hoxd13)11Ddu mutation (0 available); any Del(2Hoxd8-Hoxd13)11Ddu mutation (0 available)
Del(6Hoxa)1Ddu mutation (0 available); any Del(6Hoxa)1Ddu mutation (0 available)
Hoxatm1Ddu mutation (0 available); any Hoxa mutation (0 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal forelimb zeugopod morphology ( J:114566 )
• no genuine forearm in newborn mice
abnormal limb development ( J:114566 )
• abnormal segmented cartilaginous condensation is present, instead of digits, radii, or ulnae
abnormal digit development ( J:114566 )
• no genuine digits form on forelimb in newborn mice

skeleton




Genotype
MGI:5469822
cx3
Allelic
Composition		 Dp(2Evx2-Atf2)59Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic
Background		 involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
limbs/digits/tail phenotype ( J:192248 )
N
• normal limb phenotype




Genotype
MGI:5469823
cx4
Allelic
Composition		 Dp(2Lnp-Atf2)60Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic
Background		 involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
limbs/digits/tail phenotype ( J:192248 )
N
• normal limb phenotype




Genotype
MGI:5469824
cx5
Allelic
Composition		 Dp(2Evx2)61Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic
Background		 involves: 129P2/OlaHsd * 129S1/Sv * 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal digit morphology ( J:192248 )
• incomplete penetrance of digit I defects
abnormal phalanx morphology ( J:192248 )
• shortened digit II with a missing phalange
brachydactyly ( J:192248 )
• shortened digit II with a missing phalange

skeleton
abnormal phalanx morphology ( J:192248 )
• shortened digit II with a missing phalange




Genotype
MGI:5469826
cx6
Allelic
Composition		 Del(2Atf2)50Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic
Background		 involves: 129P2/OlaHsd * 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal phalanx morphology ( J:192248 )
• shortened digit II with a missing phalange
brachydactyly ( J:192248 )
• shortened digit II with a missing phalange

skeleton
abnormal phalanx morphology ( J:192248 )
• shortened digit II with a missing phalange




Genotype
MGI:5469825
cx7
Allelic
Composition		 Dp(2Lnp)62Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic
Background		 involves: 129S1/Sv * 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
limbs/digits/tail phenotype ( J:192248 )
N
• normal limb phenotype




Genotype
MGI:5305758
cx8
Allelic
Composition		 Del(2Lnp)48Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal digit morphology ( J:178930 )
• shortening of digit V with missing middle phalange
abnormal phalanx morphology ( J:178930 )
• absence of the middle phalange of digit V

skeleton
abnormal phalanx morphology ( J:178930 )
• absence of the middle phalange of digit V




Genotype
MGI:5305759
cx9
Allelic
Composition		 Del(2)49Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal digit morphology ( J:178930 )
• incomplete penetrance of malformations of digit I




Genotype
MGI:5305760
cx10
Allelic
Composition		 Del(2Evx2)51Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal digit morphology ( J:178930 )
• shortening of digits II and V




Genotype
MGI:5305762
cx11
Allelic
Composition		 Del(2Atf2)52Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal digit morphology ( J:178930 )
• all digits are malformed at birth
abnormal phalanx morphology ( J:178930 )
• all digits have only 2 phalanges

skeleton
abnormal phalanx morphology ( J:178930 )
• all digits have only 2 phalanges




Genotype
MGI:5305764
cx12
Allelic
Composition		 Del(2Evx2-Atf2)53Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal phalanx morphology ( J:178930 )
• missing or fused phalanges

skeleton
abnormal phalanx morphology ( J:178930 )
• missing or fused phalanges




Genotype
MGI:5305767
cx13
Allelic
Composition		 Del(2Atf2)50Ddu/Del(2Hoxd8-Hoxd13)11Ddu
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
abnormal digit morphology ( J:178930 )
• shortening of digit II at birth, with a missing phalange
abnormal phalanx morphology ( J:178930 )
• missing phalange in digit II

skeleton
abnormal phalanx morphology ( J:178930 )
• missing phalange in digit II




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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory