Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wnt3atm1(cre)Eag mutation
(0 available);
any
Wnt3a mutation
(25 available)
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nervous system
N |
• homozygous or heterozygous mice do not show any signs Wnt3a signaling from the hem, such as a shrunken dentate gyrus
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(DTA)Riet mutation
(0 available);
any
Gt(ROSA)26Sor mutation
(944 available)
Relnrl mutation
(3 available);
any
Reln mutation
(209 available)
Wnt3atm1(cre)Eag mutation
(0 available);
any
Wnt3a mutation
(25 available)
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nervous system
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• number of Cajal-Retzius cells in the cortical marginal zone is reduced by 35% at P0
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(DTA)Riet mutation
(0 available);
any
Gt(ROSA)26Sor mutation
(944 available)
Relnrl mutation
(3 available);
any
Reln mutation
(209 available)
Trp73tm1(cre)Agof mutation
(0 available);
any
Trp73 mutation
(42 available)
Wnt3atm1(cre)Eag mutation
(0 available);
any
Wnt3a mutation
(25 available)
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nervous system
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• number of Cajal-Retzius cells (CRc) in the cortical marginal zone is reduced by 84% at P0
• nearly all CRc in the hippocampal formation are ablated
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb1tm1Mll mutation
(1 available);
any
Itgb1 mutation
(59 available)
Wnt3atm1(cre)Eag mutation
(0 available);
any
Wnt3a mutation
(25 available)
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nervous system
N |
• at E15.5, mice exhibit normal Caja-Retzius localization and radial glia scaffold
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