All Phenotypes Chst3<tm1Dgen> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Chst3^tm1Dgen
targeted mutation 1, Deltagen
MGI:3604509

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Chst3^tm1Dgen/Chst3^tm1Dgen	involves: 129P2/OlaHsd * C57BL/6	MGI:3606703

Allelic Composition	Chst3^tm1Dgen/Chst3^tm1Dgen
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chst3^tm1Dgen mutation (1 available); any Chst3 mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased coping response ( J:101679 )

• decreased time immobile during a tail suspension test

decreased locomotor activity ( J:101679 )

nervous system

decreased prepulse inhibition ( J:101679 )

• decreased prepulse inhibition

• stimulus processing deficit similar to schizophrenia

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
schizophrenia		DOID:5419	OMIM:181500	J:101679

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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