Phenotypes associated with this allele

• Allele Symbol: Casz1⁺
• Allele Name: wild type
• Allele ID: MGI:3579787
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Casz1^tm1b(EUCOMM)Hmgu/Casz1^+	C57BL/6N-Casz1^tm1b(EUCOMM)Hmgu/H	MGI:5759129
ht2	Casz1^tm2(cre/ERT2)Flc/Casz1^+	involves: 129P2/OlaHsd	MGI:5811813
cn3	Casz1^tm1.1Flc/Casz1^+ Nkx2-5^tm1(cre)Rjs/Nkx2-5^+	involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL	MGI:5811817

Genotype
MGI:5759129

ht1

• Allelic Composition: Casz1^{tm1b(EUCOMM)Hmgu}/Casz1⁺
• Genetic Background: C57BL/6N-Casz1^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0679_6_D09

Data Sources

IMPC Data for Casz1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

shortened QT interval ( J:211773 )

IMPC - HAR

vision/eye

persistence of hyaloid vascular system ( J:211773 )

♂

IMPC - HAR

Genotype
MGI:5811813

ht2

• Allelic Composition: Casz1^{tm2(cre/ERT2)Flc}/Casz1⁺
• Genetic Background: involves: 129P2/OlaHsd

normal phenotype

no abnormal phenotype detected ( J:221324 )

• heterozygotes are viable, fertile, and show no obvious phenotypic abnormalities; mice were crossed to a tomato reporter for lineage tracing of Casz1-expressing cells in the embryonic heart

Genotype
MGI:5811817

cn3

• Allelic Composition: Casz1^tm1.1Flc/Casz1⁺; Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺
• Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL

normal phenotype

no abnormal phenotype detected ( J:221324 )

• mice are viable, fertile and show no obvious phenotypic abnormalities