About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Abl1tm1Ajk
targeted mutation 1, Anthony J Koleske
MGI:3525886
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Abl1tm1Ajk/Abl1tm1Ajk
Abl2tm1Ajk/Abl2tm1Ajk
Tg(Nes-cre)1Kag/? 		involves: 129S4/SvJae MGI:3583883


Genotype
MGI:3583883
cn1
Allelic
Composition		 Abl1tm1Ajk/Abl1tm1Ajk
Abl2tm1Ajk/Abl2tm1Ajk
Tg(Nes-cre)1Kag/?
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Abl1tm1Ajk mutation (1 available); any Abl1 mutation (92 available)
Abl2tm1Ajk mutation (0 available); any Abl2 mutation (79 available)
Tg(Nes-cre)1Kag mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:99296 )
N
• only 35% of the expected Mendelian numbers are born
• those that were born survived well into adulthood

nervous system
abnormal cerebral cortex pyramidal cell morphology ( J:99296 )
• smaller dendrite arbors resulting in more densely packed neurons in all layers of cortex in 6-8 weeks old mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory