Abl1^tm1Ajk
Targeted Allele Detail

Summary

• Symbol: Abl1^tm1Ajk
• Name: c-abl oncogene 1, non-receptor tyrosine kinase; targeted mutation 1, Anthony J Koleske
• MGI ID: MGI:3525886
• Synonyms: abl^flox, c-Abl^flox
• Gene: Abl1 Location: Chr2:31578388-31694239 bp, + strand Genetic Position: Chr2, 21.86 cM, cytoband B
• Alliance: Abl1^tm1Ajk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99296
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites were inserted to flank exon 5. (J:99296)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Abl1 Mutation: 92 strains or lines available

References

• Original: J:99296 Moresco EM, et al., Integrin-mediated dendrite branch maintenance requires Abelson (Abl) family kinases. J Neurosci. 2005 Jun 29;25(26):6105-18
• All: 18 reference(s)