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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hectd1+
wild type
MGI:2672968
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Hectd1opm/Hectd1+ C3.B6-Hectd1opm MGI:3707221
ht2
 		Hectd1tm1b(EUCOMM)Hmgu/Hectd1+ C57BL/6N-Hectd1tm1b(EUCOMM)Hmgu/Nju MGI:6262611
ht3
 		Hectd1Gt(XC266)Byg/Hectd1+ involves: 129P2/OlaHsd MGI:3707233


Genotype
MGI:3707221
ht1
Allelic
Composition		 Hectd1opm/Hectd1+
Genetic
Background		 C3.B6-Hectd1opm
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hectd1opm mutation (0 available); any Hectd1 mutation (141 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
exencephaly ( J:122594 )
• between E9.5 and 12.5, about 5% of embryos exhibit cranial neural tube closure defects from mid- and hindbrain
• exencephaly is less severe than in homozygotes




Genotype
MGI:6262611
ht2
Allelic
Composition		 Hectd1tm1b(EUCOMM)Hmgu/Hectd1+
Genetic
Background		 C57BL/6N-Hectd1tm1b(EUCOMM)Hmgu/Nju
Cell Lines HEPD0728_7_C08
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hectd1tm1b(EUCOMM)Hmgu mutation (0 available); any Hectd1 mutation (141 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system

homeostasis/metabolism

immune system

integument

pigmentation




Genotype
MGI:3707233
ht3
Allelic
Composition		 Hectd1Gt(XC266)Byg/Hectd1+
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hectd1Gt(XC266)Byg mutation (0 available); any Hectd1 mutation (141 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
exencephaly ( J:122594 )
• between E9.5 and 12.5, 20% of embryos exhibit cranial neural tube closure defects




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory