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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Chuk+
wild type
MGI:2432577
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Chukem1(IMPC)Ccpcz/Chuk+ C57BL/6NCrl-Chukem1(IMPC)Ccpcz/Ccpcz MGI:7414834
cx2
 		Chuktm1Mka/Chuk+
SfnEr/SfnEr 		involves: 129S1/Sv * 129X1/SvJ MGI:5426900
cx3
 		Chuktm1Mka/Chuk+
Irf6tm1Mjd/Irf6tm1Mjd 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5426904


Genotype
MGI:7414834
ht1
Allelic
Composition		 Chukem1(IMPC)Ccpcz/Chuk+
Genetic
Background		 C57BL/6NCrl-Chukem1(IMPC)Ccpcz/Ccpcz
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chukem1(IMPC)Ccpcz mutation (1 available); any Chuk mutation (51 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
abnormal tooth color ( J:211773 )
IMPC - CCP-IMG

endocrine/exocrine glands
enlarged thymus ( J:211773 )
IMPC - CCP-IMG
small testis ( J:211773 )
IMPC - CCP-IMG

growth/size/body
abnormal tooth morphology ( J:211773 )
IMPC - CCP-IMG
abnormal tooth color ( J:211773 )
IMPC - CCP-IMG

hematopoietic system
enlarged thymus ( J:211773 )
IMPC - CCP-IMG

immune system
enlarged thymus ( J:211773 )
IMPC - CCP-IMG
enlarged lymph nodes ( J:211773 )
IMPC - CCP-IMG

reproductive system
small testis ( J:211773 )
IMPC - CCP-IMG
hydrometra ( J:211773 )
IMPC - CCP-IMG

skeleton
abnormal tooth color ( J:211773 )
IMPC - CCP-IMG

vision/eye
microphthalmia ( J:211773 )
IMPC - CCP-IMG




Genotype
MGI:5426900
cx2
Allelic
Composition		 Chuktm1Mka/Chuk+
SfnEr/SfnEr
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chuktm1Mka mutation (0 available); any Chuk mutation (51 available)
SfnEr mutation (1 available); any Sfn mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
craniofacial phenotype ( J:184926 )
N
• mice exhibit normal teeth and molar tooth germ




Genotype
MGI:5426904
cx3
Allelic
Composition		 Chuktm1Mka/Chuk+
Irf6tm1Mjd/Irf6tm1Mjd
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chuktm1Mka mutation (0 available); any Chuk mutation (51 available)
Irf6tm1Mjd mutation (0 available); any Irf6 mutation (24 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
abnormal incisor morphology ( J:184926 )
• the evaginating incisor phenotype is neither attenuated or worsened compared with Irf6tm1Mjd homozygotes

growth/size/body
abnormal incisor morphology ( J:184926 )
• the evaginating incisor phenotype is neither attenuated or worsened compared with Irf6tm1Mjd homozygotes

skeleton
abnormal incisor morphology ( J:184926 )
• the evaginating incisor phenotype is neither attenuated or worsened compared with Irf6tm1Mjd homozygotes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory