All Phenotypes Hr<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Hr⁺
wild type
MGI:2430932

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Hr^Hp/Hr⁺	BALB/cJ-Hr^Hp	MGI:3851928
ht2	Hr^N/Hr⁺	involves: ORNL:STOCK A^w/a Oca2^p	MGI:4414800
cx3	Adam10^Pied/Adam10⁺ Hr^hr/Hr⁺	HRA/SkhKcl-Adam10^Pied Hr^Hr	MGI:6163712

Allelic Composition	Hr^Hp/Hr⁺
Genetic Background	BALB/cJ-Hr^Hp

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hr^Hp mutation (0 available); any Hr mutation (86 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Hair coat abnormalities in Hr^Hp/Hr⁺ and Hr^Hp/Hr^Hp mice

integument

alopecia ( J:150720 )

• mice lose their hair as they age and are bald by 40 weeks

short hair ( J:150720 )

sparse hair ( J:150720 )

abnormal vibrissa follicle morphology ( J:150720 )

• vibrissa hair follicles exhibit an intermediate phenotype

abnormal vibrissa morphology ( J:150720 )

• mice exhibit an intermediate vibrissa phenotype

• vibrissa are shorter than in wild-type mice

abnormal vibrissa number ( J:150720 )

• fewer

wavy vibrissae ( J:150720 )

• slightly

abnormal epidermal layer morphology ( J:150720 )

• epidermal epithelial cell growth is reduced and cavernous sinus is expanded compared to in wild-type mice

epidermal cyst ( J:150720 )

• at P210, mice develop cysts in the skin

wrinkled skin ( J:150720 )

• very mild

growth/size/body

epidermal cyst ( J:150720 )

• at P210, mice develop cysts in the skin

Allelic Composition	Hr^N/Hr⁺
Genetic Background	involves: ORNL:STOCK A^w/a Oca2^p

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hr^N mutation (2 available); any Hr mutation (86 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat appearance ( J:7103 )

• a fuzzy and thin coat is seen at 10 days of age and persists

abnormal hair growth ( J:7103 )

• adults undergo repeated hair loss and regrowth but are never entirely bare

sparse hair ( J:7103 )

• fuzzy, thin coat develops at about 10 days of age and persists

abnormal vibrissa morphology ( J:7103 )

curly vibrissae ( J:7103 )

short vibrissae ( J:7103 )

shiny skin ( J:7103 )

• easily distinguished at 5 days of age

thin skin ( J:7103 )

• noticed as early as 5 days of age

Allelic Composition	Adam10^Pied/Adam10⁺ Hr^hr/Hr⁺
Genetic Background	HRA/SkhKcl-Adam10^Pied Hr^Hr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adam10^Pied mutation (0 available); any Adam10 mutation (39 available)
Hr^hr mutation (17 available); any Hr mutation (86 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

pigmentation phenotype ( J:262499 )

N	• no macules are observed in trunk hair

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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