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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Glrb+
wild type
MGI:2430631
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Glrbspa/Glrb+ B6C3Fe a/a-Glrbspa/J MGI:3622189
ht2
 		Glrbem1(IMPC)Tcp/Glrb+ C57BL/6NCrl-Glrbem1(IMPC)Tcp/Tcp MGI:6262528


Genotype
MGI:3622189
ht1
Allelic
Composition		 Glrbspa/Glrb+
Genetic
Background		 B6C3Fe a/a-Glrbspa/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Glrbspa mutation (2 available); any Glrb mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
impaired fertilization ( J:107699 )
• in mutants, the zona pellucida-initiated acrosome reaction is significantly decreased compared to wild-type
impaired acrosome reaction ( J:107699 )
• the zona pellucida-initiated acrosome reaction is significantly decreased compared to wild-type




Genotype
MGI:6262528
ht2
Allelic
Composition		 Glrbem1(IMPC)Tcp/Glrb+
Genetic
Background		 C57BL/6NCrl-Glrbem1(IMPC)Tcp/Tcp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Glrbem1(IMPC)Tcp mutation (2 available); any Glrb mutation (35 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological

cardiovascular system

growth/size/body
increased heart weight ( J:211773 )
IMPC - TCP
increased spleen weight ( J:211773 )
IMPC - TCP

hematopoietic system

homeostasis/metabolism

immune system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory