Phenotypes associated with this allele

• Allele Symbol: Tg(tetO-Foxg1)1Lai
• Allele Name: transgene insertion 1, Eseng Lai
• Allele ID: MGI:2388675
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Foxg1^tm1(tTA)Lai/Foxg1^tm1M Tg(tetO-Foxg1)1Lai/0	involves: 129S1/Sv * C57BL/6	MGI:2451132

Genotype
MGI:2451132

cx1

• Allelic Composition: Foxg1^tm1(tTA)Lai/Foxg1^tm1M; Tg(tetO-Foxg1)1Lai/0
• Genetic Background: involves: 129S1/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:78115 )

N • size of the neocortex and proliferation of progenitor cells throughout the dorsal telencephalon are restored to normal levels by expression of the mutant protein

abnormal neuron differentiation ( J:78115 )

• accelerated neuronal differentiation in the neocortical neuroepithelium resulting in a marked increase in the thickness of the mantle

abnormal neural tube mantle layer morphology ( J:78115 )

• thickness of the mantle zone in the dorsal telencephalon is increased due to accelerated neuronal differentiation

abnormal basal ganglion morphology ( J:78115 )

• absent

abnormal telencephalon morphology ( J:78115 )

• dorsomedial telencephalon is abnormal

embryo

abnormal neural tube mantle layer morphology ( J:78115 )

• thickness of the mantle zone in the dorsal telencephalon is increased due to accelerated neuronal differentiation

cellular

abnormal neuron differentiation ( J:78115 )

• accelerated neuronal differentiation in the neocortical neuroepithelium resulting in a marked increase in the thickness of the mantle