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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Eportm1.4Jtp
targeted mutation 1.4, Josef T Prchal
MGI:2386099
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Eportm1.4Jtp/Eportm1.4Jtp involves: 129P2/OlaHsd * C57BL/6 MGI:2386210
ht2
Eportm1.4Jtp/Epor+ involves: 129P2/OlaHsd * C57BL/6 MGI:2386211


Genotype
MGI:2386210
hm1
Allelic
Composition
Eportm1.4Jtp/Eportm1.4Jtp
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eportm1.4Jtp mutation (0 available); any Epor mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• increase in both early and late erythroid progenitors
• develop polycythemia within 3-6 weeks after birth
• elevated on average by 58%
• erythrocytes exhibit significant anisocytosis, especially expnaded red cell mass

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
familial erythrocytosis 1 DOID:0060652 OMIM:133100
J:67205




Genotype
MGI:2386211
ht2
Allelic
Composition
Eportm1.4Jtp/Epor+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eportm1.4Jtp mutation (0 available); any Epor mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• develop polycythemia within 3-6 weeks after birth, however do not exhibit any red blood cell morphological abnormalities

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
familial erythrocytosis 1 DOID:0060652 OMIM:133100
J:67205





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/24/2023
MGI 6.22
The Jackson Laboratory