Phenotypes associated with this allele

• Allele Symbol: Mobq5^CAST/EiJ
• Allele Name: CAST/EiJ
• Allele ID: MGI:2155132
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mobq5^CAST/EiJ/Mobq5^CAST/EiJ	B6.CAST-Mobq5^CAST/EiJ	MGI:3711206
ht2	Mobq5^CAST/EiJ/Mobq5^C57BL/6J	involves: CAST/Ei * C57BL/6J	MGI:2175355
cx3	Ldlr^tm1Her/Ldlr^tm1Her Mobq5^CAST/EiJ/Mobq5^CAST/EiJ	B6.CAST-Mobq5^CAST/EiJ	MGI:3711207

Genotype
MGI:3711206

hm1

• Allelic Composition: Mobq5^CAST/EiJ/Mobq5^CAST/EiJ
• Genetic Background: B6.CAST-Mobq5^CAST/EiJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased circulating cholesterol level ( J:116503 )

• decreased plasma cholesterol

decreased circulating free fatty acids level ( J:116503 )

• decreased plasma free fatty acids on a Western diet

decreased circulating triglyceride level ( J:116503 )

• decreased plasma triglycerides on a Western diet

abnormal glucose homeostasis ( J:116503 )

• improved glucose clearance

decreased circulating glucose level ( J:116503 )

• decreased plasma glucose on a Western diet

behavior/neurological

increased food intake ( J:116503 )

• increased food consumption on a Western diet

Genotype
MGI:2175355

ht2

• Allelic Composition: Mobq5^CAST/EiJ/Mobq5^C57BL/6J
• Genetic Background: involves: CAST/Ei * C57BL/6J

adipose tissue

decreased white adipose tissue amount ( J:48038 )

homeostasis/metabolism

decreased triglyceride lipase activity ( J:48038 )

• decreased hepatic lipase activity

Genotype
MGI:3711207

cx3

• Allelic Composition: Ldlr^tm1Her/Ldlr^tm1Her; Mobq5^CAST/EiJ/Mobq5^CAST/EiJ
• Genetic Background: B6.CAST-Mobq5^CAST/EiJ

homeostasis/metabolism

abnormal circulating VLDL cholesterol level ( J:116503 )

decreased circulating cholesterol level ( J:116503 )

• decreased plasma cholesterol

• decreased unesterified cholesterol

decreased circulating HDL cholesterol level ( J:116503 )

decreased circulating LDL cholesterol level ( J:116503 )