All Phenotypes Nos2<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nos2⁺
wild type
MGI:2152807

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Apc^Min/Apc⁺ Nos2^tm1Lau/Nos2⁺	B6.Cg-Nos2^tm1Lau Apc^Min	MGI:3767792

Allelic Composition	Apc^Min/Apc⁺ Nos2^tm1Lau/Nos2⁺
Genetic Background	B6.Cg-Nos2^tm1Lau Apc^Min

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apc^Min mutation (12 available); any Apc mutation (154 available)
Nos2^tm1Lau mutation (8 available); any Nos2 mutation (66 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

decreased tumor growth/size ( J:73152 )

• polyp size reduced

decreased tumor incidence ( J:73152 )

• 68% of tumor incidence observed in controls

• multiplicity of tumors reduced to about 33% of control level

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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