All Phenotypes Tyr<c-ch> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tyr^c-ch
chinchilla
MGI:1855977

Summary

14 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tyr^c-ch/Tyr^c-ch	involves: C57BL/6	MGI:3794760
ht2	Tyr^c-42H/Tyr^c-ch	involves: 101/H * C3H/HeH	MGI:5304166
ht3	Tyr^c-ch/Tyr^c-ch38H	involves: 101/H * C3H/HeH	MGI:5304163
ht4	Tyr^c-43H/Tyr^c-ch	involves: 101/H * C3H/HeH	MGI:5304168
ht5	Tyr^c-112K/Tyr^c-ch	involves: 101/RI * C3Hf/RI * St.2A	MGI:3794732
ht6	Tyr^c-40H/Tyr^c-ch	involves: C3H/HeH	MGI:5304164
ht7	Tyr^c-a/Tyr^c-ch	involves: C3H/HeJ	MGI:4360397
ht8	Tyr^cm1OR/Tyr^c-ch	involves: C3H/Rl	MGI:4431055
cx9	Mecp2^em1Dkatz/Mecp2⁺ Tyr^c-ch/Tyr^c-ch	FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J	MGI:6159334
cx10	Mecp2^em1Dkatz/Mecp2^em1Dkatz Tyr^c-ch/Tyr^c-ch	FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J	MGI:6159335
cx11	Mecp2^em1Dkatz/Y Tyr^c-ch/Tyr^c-ch	FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J	MGI:6159336
cx12	Tyr^c-ch/Del(7)Tyr^c-3H	involves: 101/H * C3H/HeH	MGI:4431256
cx13	Tyr^c-ch/Del(7)Tyr^c-6H	involves: 101/H * C3H/HeH	MGI:4843178
cx14	A/A Tyr^c-ch/Tyr^c-ch	Not Specified	MGI:5460836

Allelic Composition	Tyr^c-ch/Tyr^c-ch
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyr^c-ch mutation (79 available); any Tyr mutation (375 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

diluted coat color ( J:6611 )

• mice have a grey coat color

• the amount of melanin found in anagen hairbulbs is reduced by more than 30% compared to wild-type mice

integument

diluted coat color ( J:6611 )

• mice have a grey coat color

• the amount of melanin found in anagen hairbulbs is reduced by more than 30% compared to wild-type mice

Allelic Composition	Tyr^c-42H/Tyr^c-ch
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyr^c-42H mutation (0 available); any Tyr mutation (375 available)
Tyr^c-ch mutation (79 available); any Tyr mutation (375 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

diluted coat color ( J:179802 )

• mice resemble Tyr^c/Tyr^c-ch heterozygotes

integument

diluted coat color ( J:179802 )

• mice resemble Tyr^c/Tyr^c-ch heterozygotes

Allelic Composition	Tyr^c-ch/Tyr^c-ch38H
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyr^c-ch mutation (79 available); any Tyr mutation (375 available)
Tyr^c-ch38H mutation (0 available); any Tyr mutation (375 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

diluted coat color ( J:179802 )

integument

diluted coat color ( J:179802 )

Allelic Composition	Tyr^c-43H/Tyr^c-ch
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyr^c-43H mutation (0 available); any Tyr mutation (375 available)
Tyr^c-ch mutation (79 available); any Tyr mutation (375 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

absent coat pigmentation ( J:179802 )

• albino with pink eyes

absent eye pigmentation ( J:179802 )

• albino with pink eyes

vision/eye

absent eye pigmentation ( J:179802 )

• albino with pink eyes

integument

absent coat pigmentation ( J:179802 )

• albino with pink eyes

Allelic Composition	Tyr^c-112K/Tyr^c-ch
Genetic Background	involves: 101/RI * C3Hf/RI * St.2A

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyr^c-112K mutation (1 available); any Tyr mutation (375 available)
Tyr^c-ch mutation (79 available); any Tyr mutation (375 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

diluted coat color ( J:113951 )

• mice have a chinchilla coat color

integument

diluted coat color ( J:113951 )

• mice have a chinchilla coat color

Allelic Composition	Tyr^c-40H/Tyr^c-ch
Genetic Background	involves: C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyr^c-40H mutation (0 available); any Tyr mutation (375 available)
Tyr^c-ch mutation (79 available); any Tyr mutation (375 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

diluted coat color ( J:179802 )

• mice resemble Tyr^c/Tyr^c-ch heterozygotes

integument

diluted coat color ( J:179802 )

• mice resemble Tyr^c/Tyr^c-ch heterozygotes

Allelic Composition	Tyr^c-a/Tyr^c-ch
Genetic Background	involves: C3H/HeJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyr^c-a mutation (2 available); any Tyr mutation (375 available)
Tyr^c-ch mutation (79 available); any Tyr mutation (375 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:14994 )

• coat color is intermediate between chinchilla and acromelanic homozygotes with a very darkly pigmented anal region

integument

abnormal coat/hair pigmentation ( J:14994 )

• coat color is intermediate between chinchilla and acromelanic homozygotes with a very darkly pigmented anal region

Allelic Composition	Tyr^cm1OR/Tyr^c-ch
Genetic Background	involves: C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyr^c-ch mutation (79 available); any Tyr mutation (375 available)
Tyr^cm1OR mutation (1 available); any Tyr mutation (375 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:38209 )

mottled coat ( J:38209 )

• areas of white and wild-type agouti fur

integument

abnormal coat/hair pigmentation ( J:38209 )

mottled coat ( J:38209 )

• areas of white and wild-type agouti fur

Allelic Composition	Mecp2^em1Dkatz/Mecp2⁺ Tyr^c-ch/Tyr^c-ch
Genetic Background	FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2^em1Dkatz mutation (0 available); any Mecp2 mutation (38 available)
Tyr^c-ch mutation (79 available); any Tyr mutation (375 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal locomotor behavior ( J:101977 )

• females exhibit a locomotor phenotype onset as early as 14 weeks of age

reproductive system

reproductive system phenotype ( J:101977 )

N	• fertility is normal

Allelic Composition	Mecp2^em1Dkatz/Mecp2^em1Dkatz Tyr^c-ch/Tyr^c-ch
Genetic Background	FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

female infertility ( J:101977 )

Allelic Composition	Mecp2^em1Dkatz/Y Tyr^c-ch/Tyr^c-ch
Genetic Background	FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:101977 )

• males die by 10 weeks of age

Allelic Composition	Tyr^c-ch/Del(7)Tyr^c-3H
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7)Tyr^c-3H mutation (0 available); any Del(7)Tyr^c-3H mutation (0 available)
Tyr^c-ch mutation (79 available); any Tyr mutation (375 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:5063 )

diluted coat color ( J:5063 )

• the coat color is intermediate between that expected for an albino mouse and a mouse homozygous for chinchilla

integument

abnormal coat/hair pigmentation ( J:5063 )

diluted coat color ( J:5063 )

• the coat color is intermediate between that expected for an albino mouse and a mouse homozygous for chinchilla

Allelic Composition	Tyr^c-ch/Del(7)Tyr^c-6H
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7)Tyr^c-6H mutation (1 available); any Del(7)Tyr^c-6H mutation (0 available)
Tyr^c-ch mutation (79 available); any Tyr mutation (375 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:5741 )

diluted coat color ( J:5741 )

• these mice are noticeably lighter in color than mice that are homozygous chinchilla

integument

abnormal coat/hair pigmentation ( J:5741 )

diluted coat color ( J:5741 )

• these mice are noticeably lighter in color than mice that are homozygous chinchilla

Allelic Composition	A/A Tyr^c-ch/Tyr^c-ch
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A mutation (19 available); any a mutation (463 available)
Tyr^c-ch mutation (79 available); any Tyr mutation (375 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat appearance ( J:36414 )

• the contrasted effects of this genotype on eumelanin and phaeomelanin produces a grizzled color pattern or chinchilla effect

abnormal coat/hair pigmentation ( J:36414 )

• reduced melanin content alters the wild-type agouti color to gray

abnormal hair follicle pheomelanosome pheomelanin content ( J:36414 )

• in this genotype yellow pigment in the hair shaft is reduced or absent

pigmentation

abnormal coat/hair pigmentation ( J:36414 )

• reduced melanin content alters the wild-type agouti color to gray

abnormal hair follicle pheomelanosome pheomelanin content ( J:36414 )

• in this genotype yellow pigment in the hair shaft is reduced or absent

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