Carinh^em1Cvsg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Carinh^em1Cvsg
• Name: colitis associated IRF1 antisense regulator of intestinal homeostasis; endonuclease-mediated mutation 1, Coen van Solingen
• MGI ID: MGI:8473892
• Gene: Carinh Location: Chr11:53676315-53750082 bp, - strand Genetic Position: Chr11, 32.0 cM
• Alliance: Carinh^em1Cvsg page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas-mediated targeting of exon 1 generated an 82 bp deletion and premature termination. (J:370090)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Carinh Mutation: 5 strains or lines available

References

• Original: J:370090 Cyr Y, et al., lncRNA CARINH regulates expression and function of innate immune transcription factor IRF1 in macrophages. Life Sci Alliance. 2025 Mar;8(3)
• All: 1 reference(s)