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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Carinhem1Cvsg
endonuclease-mediated mutation 1, Coen van Solingen
MGI:8473892
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Carinhem1Cvsg/Carinhem1Cvsg Not Specified MGI:8473897


Genotype
MGI:8473897
hm1
Allelic
Composition		 Carinhem1Cvsg/Carinhem1Cvsg
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Carinhem1Cvsg mutation (0 available); any Carinh mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
increased susceptibility to viral infection induced morbidity/mortality ( J:370090 )
• in mice infected by influenza A/PR8/34 virus

immune system
increased susceptibility to viral infection ( J:370090 )
• mice infected by influenza A/PR8/34 virus exhibit reduced inflammation response and increased mortality compared with similarly treated wild-type mice
increased susceptibility to viral infection induced morbidity/mortality ( J:370090 )
• in mice infected by influenza A/PR8/34 virus




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/13/2026
MGI 6.29 		The Jackson Laboratory