Tmem217^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmem217^em1Osb
• Name: transmembrane protein 217; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:8325211
• Gene: Tmem217 Location: Chr17:29744983-29768567 bp, - strand Genetic Position: Chr17, 15.42 cM, cytoband B1
• Alliance: Tmem217^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 1071 bp large deletion of the coding region. (J:383008)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem217 Mutation: 13 strains or lines available

References

• Original: J:383008 Iida-Norita R, et al., Formation of a complex between TMEM217 and the sodium-proton exchanger SLC9C1 is crucial for mouse sperm motility and male fertility. Proc Natl Acad Sci U S A. 2025 Oct 21;122(42):e2513924122
• All: 1 reference(s)