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Paupartm1.1Suss
Targeted Allele Detail
Summary
Symbol: Paupartm1.1Suss
Name: Pax6 upstream antisense RNA; targeted mutation 1.1, Lori Sussel
MGI ID: MGI:8213455
Gene: Paupar  Location: Chr2:105488207-105491688 bp, - strand  Genetic Position: Chr2, Syntenic
Alliance: Paupartm1.1Suss page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:282894
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA construct containing an H2B-GFP fusion reporter gene and an frt flanked neo cassette replaced a 3.5 kb region including exons 1-3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:282894)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Paupar Mutation:  3 strains or lines available
References
Original:  J:282894 Singer RA, et al., The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function. Cell Metab. 2019 Dec 3;30(6):1091-1106.e8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory