Tent5b^em3Adki
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tent5b^em3Adki
• Name: terminal nucleotidyltransferase 5B; endonuclease-mediated mutation 3, Andrzej Dziembowski
• MGI ID: MGI:8164233
• Synonyms: Tent5b^GFP
• Gene: Tent5b Location: Chr4:133207443-133215249 bp, + strand Genetic Position: Chr4, 66.25 cM
• Alliance: Tent5b^em3Adki page

Mutation origin

• Strain of Origin: (C57BL/6JTar x CBA/WTar)F1

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• CRISPR/Cas9 technology inserted a GFP tag at the C-terminus. (J:360869)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tent5b Mutation: 17 strains or lines available

References

• Original: J:360869 Brouze M, et al., TENT5-mediated polyadenylation of mRNAs encoding secreted proteins is essential for gametogenesis in mice. Nat Commun. 2024 Jun 22;15(1):5331
• All: 1 reference(s)