Adamdec1^em1Xav
Endonuclease-mediated Allele Detail

Summary

• Symbol: Adamdec1^em1Xav
• Name: ADAM-like, decysin 1; endonuclease-mediated mutation 1, Ramnik J Xavier
• MGI ID: MGI:7428418
• Gene: Adamdec1 Location: Chr14:68800829-68819535 bp, - strand Genetic Position: Chr14, 35.69 cM
• Alliance: Adamdec1^em1Xav page

Mutation origin

• Strain of Origin: BALB/c

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-cas9 mediated recombination created a deletion spanning exons 1 and 2. (J:322223)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adamdec1 Mutation: 41 strains or lines available

References

• Original: J:322223 Jasso GJ, et al., Colon stroma mediates an inflammation-driven fibroblastic response controlling matrix remodeling and healing. PLoS Biol. 2022 Jan;20(1):e3001532
• All: 1 reference(s)