Aldh1a2^tm1.1Mbp
Targeted Allele Detail

Summary

• Symbol: Aldh1a2^tm1.1Mbp
• Name: aldehyde dehydrogenase family 1, subfamily A2; targeted mutation 1.1, Mouse Biology Program, UC Davis
• MGI ID: MGI:7327620
• Synonyms: Aldh1a2^fl
• Gene: Aldh1a2 Location: Chr9:71123071-71203525 bp, + strand Genetic Position: Chr9, 39.85 cM
• Alliance: Aldh1a2^tm1.1Mbp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:324714
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting vector inserted into intron 3 an FRT-flanked neomycin resistance cassette with a 3' UTR and into intron 4 an additional loxP site. Flp-mediated recombination removed the selection cassette and left exon 4 floxed. (J:324714)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aldh1a2 Mutation: 36 strains or lines available

References

• Original: J:324714 Beedle MT, et al., Sources of all-trans retinal oxidation independent of the aldehyde dehydrogenase 1A isozymes exist in the postnatal testis. Biol Reprod. 2019 Feb 1;100(2):547-560
• All: 2 reference(s)