Zar1^em1Hyfn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zar1^em1Hyfn
• Name: zygote arrest 1; endonuclease-mediated mutation 1, Heng-Yu Fan
• MGI ID: MGI:6696065
• Gene: Zar1 Location: Chr5:72734456-72738707 bp, - strand Genetic Position: Chr5, 38.44 cM
• Alliance: Zar1^em1Hyfn page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 1 deleted 12 bp. (J:282460)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zar1 Mutation: 17 strains or lines available

References

• Original: J:282460 Rong Y, et al., ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation. Nucleic Acids Res. 2019 Dec 2;47(21):11387-11402
• All: 1 reference(s)