Fus^{em2(FUS*Q519I)Emcf}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fus^{em2(FUS*Q519I)Emcf}
• Name: fused in sarcoma; endonuclease-mediated mutation 2, Elizabeth MC Fisher
• MGI ID: MGI:6403272
• Gene: Fus Location: Chr7:127565276-127581204 bp, + strand Genetic Position: Chr7, 69.87 cM
• Alliance: Fus^{em2(FUS*Q519I)Emcf} page

Mutation origin

• Strain of Origin: B6.129(Cg)-Fus^{tm3.1(FUS)Emcf}/EmcfH

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: CRISPR-retargeting of wild-type human gene Fus^{tm3.1(FUS)Emcf} insertion introduced a four nucleotide deletion and a Q519I frameshift in the humanised wildtype FUS allele. (J:90559)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fus Mutation: 51 strains or lines available

References

• Original: J:90559 The Mammalian Genetics Unit at Harwell, Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK. Unpublished. 2004-2013
• All: 1 reference(s)