Hdnr^em2Phg
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hdnr^em2Phg
• Name: Hand2 downstream lncRNA; endonuclease-mediated mutation 2, Phillip Grote
• MGI ID: MGI:6400489
• Synonyms: Hdn^em2Phg
• Gene: Hdnr Location: Chr8:57785470-57807615 bp, + strand Genetic Position: Chr8, 29.8 cM

Mutation origin

• Germline Transmission: Unknown
• Parent Cell Line: F1H4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NTac)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISP-targeting deleted 25,956 bp (chr8: 57,331,198-57,357,153; mm10). (J:284123)

Expression

In Mice Carrying this Mutation:

10 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hdnr Mutation: 0 strains or lines available

Notes

This allele was generated in ES cells at the same time as 5033428I22Rik^em3Phg.

References

• Original: J:284123 Ritter N, et al., The lncRNA Locus Handsdown Regulates Cardiac Gene Programs and Is Essential for Early Mouse Development. Dev Cell. 2019 Sep 9;50(5):644-657.e8
• All: 1 reference(s)