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Hdnrem3Phg
Endonuclease-mediated Allele Detail
Summary
Symbol: Hdnrem3Phg
Name: Hand2 downstream lncRNA; endonuclease-mediated mutation 3, Phillip Grote
MGI ID: MGI:6400490
Synonyms: Hdnem3Phg
Gene: Hdnr  Location: Chr8:57785470-57807615 bp, + strand  Genetic Position: Chr8, 29.8 cM
Alliance: Hdnrem3Phg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:284123
Parent Cell Line:  F1H4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NTac)F1
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    CRISPR-targeting deleted 25,724 bp (chr8: 57,331,180-57,356,903; mm10). (J:284123)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hdnr Mutation:  0 strains or lines available
Notes
This allele was generated in ES cells at the same time as 5033428I22Rikem2Phg.
References
Original:  J:284123 Ritter N, et al., The lncRNA Locus Handsdown Regulates Cardiac Gene Programs and Is Essential for Early Mouse Development. Dev Cell. 2019 Sep 9;50(5):644-657.e8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory