Del(7Saa3-Saa2)738Lvh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(7Saa3-Saa2)738Lvh
• Name: deletion, Chr 7, Lora Hooper 738
• MGI ID: MGI:6393613
• Synonyms: Saa^-
• Gene: Del(7Saa3-Saa2)738Lvh Location: unknown Genetic Position: Chr7, Syntenic

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intergenic deletion, Intragenic deletion
• Del(7Saa3-Saa2)738Lvh involves 4 genes/genome features (Saa3, Saa4, Saa1 ...) View all
• Mutation details: CRISPR/Cas9 genome editing is used to generate guide RNAs that target regions upstream and downstream of the Saa locus and delete Saa3, Saa4, Saa1, and Saa2, respectively, clustered on mouse Chromosome 7. (J:279540)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Del(7Saa3-Saa2)738Lvh Mutation: 1 strain or line available

References

• Original: J:279540 Hu Z, et al., Molecular basis for retinol binding by serum amyloid A during infection. Proc Natl Acad Sci U S A. 2019 Sep 17;116(38):19077-19082
• All: 4 reference(s)