Del(7Fut2-Sec1)1Dzhou
Targeted Allele Detail

Summary

• Symbol: Del(7Fut2-Sec1)1Dzhou
• Name: deletion, Chr 7, Dapeng Zhou
• MGI ID: MGI:6358189
• Gene: Del(7Fut2-Sec1)1Dzhou Location: unknown Genetic Position: Chr7, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278494
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Intergenic deletion, Intragenic deletion
• Del(7Fut2-Sec1)1Dzhou involves 2 genes/genome features (Fut2, Sec1) View all
• Mutation details: BAC clone RP23-223G1 containing the mouse Fut1, Fut2, and Sec1 loci was manipulated through Red/ET recombination technology. In this deletion, a loxP-flanked neomycin cassette is used to replace a 30 kB region containing the coding region of Fut2 and Sec1. The BAC was also modified to contain a knockout of Fut1, Fut1^tm1Dzhou (J:278494)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(7Fut2-Sec1)1Dzhou Mutation: 0 strains or lines available

References

• Original: J:278494 Chen J, et al., Normal development and fertility of Fut1, Fut2, and Sec1 triple knockout mice. bioRxiv. 2019
• All: 1 reference(s)