Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Fut1tm1Dzhou
Name:	fucosyltransferase 1; targeted mutation 1, Dapeng Zhou
MGI ID:	MGI:6358187
Gene:	Fut1  Location: Chr7:45266862-45270483 bp, + strand  Genetic Position: Chr7, 29.39 cM
Alliance:	Fut1tm1Dzhou page

Germline Transmission:	Earliest citation of germline transmission: J:278494
Parent Cell Line:	iTL BA1 (ES Cell)
Strain of Origin:	(C57BL/6NTac x 129S6/SvEvTac)F1

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: BAC clone RP23-223G1 containing the mouse Fut1, Fut2, and Sec1 loci was manipulated through Red/ET recombination technology. In this targeted mutation, an FRT-flanked hygromycin resistance gene was used to replace the coding region of Fut1. The BAC was also modified to contain a deletion, Del(7Fut2-Sec1)1Dzhou (J:278494)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fut1 Mutation:	18 strains or lines available

Original:	J:278494 Chen J, et al., Normal development and fertility of Fut1, Fut2, and Sec1 triple knockout mice. bioRxiv. 2019;
All:	1 reference(s)