Tg(Ins1-Birc5)#Dabd
Transgene Detail

Summary

• Symbol: Tg(Ins1-Birc5)#Dabd
• Name: Transgene insertion, Dawn Belt Davis
• MGI ID: MGI:6197502
• Synonyms: RIP-SVV
• Transgene: Tg(Ins1-Birc5)#Dabd Location: unknown
• Alliance: Tg(Ins1-Birc5)#Dabd page

Transgene origin

• Strain of Origin: BTBR T⁺ Itpr3^tf/J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ins1-Birc5)#Dabd expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Birc5 (MGI:1203517)	rat promoter

• Mutation details: The transgene construct comprises the rat insulin promoter, the mouse cDNA and SV40 poly(A) signal sequences. The construct was microinjected into proneclei of zygotes isolated from BTBR (Black and Tan Brachyury) females. BTBR mice are models for the study of type 2 diabetes (T2DM) and autism spectrum disorder (ASD) and carry the Disc1^del, Itpr3^tf and T⁺ alleles. (J:248584)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:248584 Baan M, et al., Successful in vitro fertilization and generation of transgenics in Black and Tan Brachyury (BTBR) mice. Transgenic Res. 2016 Dec;25(6):847-854
• All: 1 reference(s)