C1qbp^tm1.1Tuch
Targeted Allele Detail

Summary

• Symbol: C1qbp^tm1.1Tuch
• Name: complement component 1, q subcomponent binding protein; targeted mutation 1, Takeshi Uchiumi
• MGI ID: MGI:5487822
• Gene: C1qbp Location: Chr11:70868672-70873852 bp, - strand Genetic Position: Chr11, 43.21 cM
• Alliance: C1qbp^tm1.1Tuch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:196232
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 3. A floxed neo cassette was inserted downstream of exon 3. Cre-mediated recombination removed exon 3 and the neo cassette. Immunofluorescence confirmed the absence of protein expression in cells. (J:196232)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any C1qbp Mutation: 23 strains or lines available

References

• Original: J:196232 Yagi M, et al., p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability. Nucleic Acids Res. 2012 Oct;40(19):9717-37
• All: 1 reference(s)