Phenotypes associated with this allele

• Allele Symbol: C1qbp^tm1.1Tuch
• Allele Name: targeted mutation 1, Takeshi Uchiumi
• Allele ID: MGI:5487822
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	C1qbp^tm1.1Tuch/C1qbp^tm1.1Tuch	involves: C57BL/6	MGI:5487824

Genotype
MGI:5487824

hm1

• Allelic Composition: C1qbp^tm1.1Tuch/C1qbp^tm1.1Tuch
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:196232 )

• mice die between E10.5 and E11.5

embryo

embryonic growth retardation ( J:196232 )

• poorly developed at E10.5

decreased embryo size ( J:196232 )

• shrunken at E10.5

cellular

decreased cell proliferation ( J:196232 )

• at E10.5, embryos exhibit poor cellular proliferation in multiple organs including the brain, heart and liver compared with wild-type mice

abnormal respiratory electron transport chain ( J:196232 )

• severe impairment in mouse embryonic fibroblasts because of impaired mitochondrial protein synthesis

hematopoietic system

anemia ( J:196232 )

• pale and anemic organs at E10.5

growth/size/body

embryonic growth retardation ( J:196232 )

• poorly developed at E10.5

decreased embryo size ( J:196232 )

• shrunken at E10.5