Del(2Hoxd1-Hoxd13)54Ddu
Targeted Allele Detail

Summary

• Symbol: Del(2Hoxd1-Hoxd13)54Ddu
• Name: deletion, Chr 2, Denis Duboule 54
• MGI ID: MGI:5318043
• Synonyms: Del(tel1-13)
• Gene: Del(2Hoxd1-Hoxd13)54Ddu Location: unknown Genetic Position: Chr2, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182758
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Intergenic deletion, Intragenic deletion
• Del(2Hoxd1-Hoxd13)54Ddu involves 15 genes/genome features (Hoxd13, Hoxd12, Hoxd11 ...) View all
• Mutation details: Produced by targeted meiotic recombination in a cross between two mice, one with an engineered loxP site telomeric to Hoxd1 and the other with a loxP site centromeric to Hoxd13, in the presence of Tg(Sycp1-cre)4Min. The entire Hoxd cluster from Hoxd1 through Hoxd13 genes is deleted. (J:182758)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(2Hoxd1-Hoxd13)54Ddu Mutation: 0 strains or lines available

References

• Original: J:182758 Tschopp P, et al., Bimodal control of Hoxd gene transcription in the spinal cord defines two regulatory subclusters. Development. 2012 Mar;139(5):929-39
• All: 1 reference(s)