Kcnk18^m1Ewis
Chemically induced Allele Detail

Summary

• Symbol: Kcnk18^m1Ewis
• Name: potassium channel, subfamily K, member 18; mutation 1, Erhard Wischmeyer
• MGI ID: MGI:5142525
• Synonyms: TRESK[G339R]
• Gene: Kcnk18 Location: Chr19:59208080-59225802 bp, + strand Genetic Position: Chr19, 54.63 cM
• Alliance: Kcnk18^m1Ewis page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a G to A transition in exon 3 that results in the amino acid substitution of arginine for glycine at position 339 (G339R). (J:100122, J:175137)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnk18 Mutation: 20 strains or lines available

References

• Original: J:175137 Dobler T, et al., TRESK two-pore-domain K+ channels constitute a significant component of background potassium currents in murine dorsal root ganglion neurones. J Physiol. 2007 Dec 15;585(Pt 3):867-79
• All: 3 reference(s)