Gt(ROSA)26Sor^{tm1.1(Lyn/Celsr1/EGFP)Rodr}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1.1(Lyn/Celsr1/EGFP)Rodr}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Tristan Rodriguez
• MGI ID: MGI:4949242
• Synonyms: ROSA26^Lyn-Celsr1
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1.1(Lyn/Celsr1/EGFP)Rodr} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:170681
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1.1(Lyn/Celsr1/EGFP)Rodr} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Celsr1 (MGI:1100883)

• Mutation details: Cre-mediated recombination removed the floxed neo stop cassette upstream of the fusion gene of Lyn, Celsr1, and EGFP. (J:170681)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1046 strains or lines available

References

• Original: J:170681 Trichas G, et al., Nodal dependent differential localisation of dishevelled-2 demarcates regions of differing cell behaviour in the visceral endoderm. PLoS Biol. 2011 Feb;9(2):e1001019
• All: 1 reference(s)