Phenotypes associated with this allele

• Allele Symbol: Gt(ROSA)26Sor^{tm1.1(Lyn/Celsr1/EGFP)Rodr}
• Allele Name: targeted mutation 1, Tristan Rodriguez
• Allele ID: MGI:4949242
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gt(ROSA)26Sor^tm1.1(Lyn/Celsr1/EGFP)Rodr/Gt(ROSA)26Sor^tm1.1(Lyn/Celsr1/EGFP)Rodr	involves: FVB/N	MGI:4949260
ht2	Gt(ROSA)26Sor^tm1.1(Lyn/Celsr1/EGFP)Rodr/Gt(ROSA)26Sor^+	involves: FVB/N	MGI:4949261

Genotype
MGI:4949260

hm1

• Allelic Composition: Gt(ROSA)26Sor^{tm1.1(Lyn/Celsr1/EGFP)Rodr}/Gt(ROSA)26Sor^{tm1.1(Lyn/Celsr1/EGFP)Rodr}
• Genetic Background: involves: FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal anterior visceral endoderm cell migration ( J:170681 )

• 6 of 11 mice exhibit anterior visceral endoderm (AVE) migration defects compared with wild-type mice

• 9 of 12 mice exhibit abnormal swirling of AVE cells compared with wild-type mice

cellular

abnormal anterior visceral endoderm cell migration ( J:170681 )

• 6 of 11 mice exhibit anterior visceral endoderm (AVE) migration defects compared with wild-type mice

• 9 of 12 mice exhibit abnormal swirling of AVE cells compared with wild-type mice

Genotype
MGI:4949261

ht2

• Allelic Composition: Gt(ROSA)26Sor^{tm1.1(Lyn/Celsr1/EGFP)Rodr}/Gt(ROSA)26Sor⁺
• Genetic Background: involves: FVB/N

embryo

abnormal anterior visceral endoderm cell migration ( J:170681 )

• 6 of 14 mice exhibit anterior visceral endoderm migration defects compared with wild-type mice

cellular

abnormal anterior visceral endoderm cell migration ( J:170681 )

• 6 of 14 mice exhibit anterior visceral endoderm migration defects compared with wild-type mice