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Gene trapped Allele Detail
Symbol: Ppm1bGt(AW0406)Wtsi
Name: protein phosphatase 1B, magnesium dependent, beta isoform; gene trap AW0406, Wellcome Trust Sanger Institute
MGI ID: MGI:3857220
Synonyms: Ppm1bd
Gene: Ppm1b  Location: Chr17:85264169-85331419 bp, + strand  Genetic Position: Chr17, 55.13 cM, cytoband E4-E5
Alliance: Ppm1bGt(AW0406)Wtsi page
Mutant Cell Line:  AW0406
Germline Transmission:  Earliest citation of germline transmission: J:243815
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Sanger Inst. Gene Trap Res.
Allele Type:    Gene trapped (Hypomorph, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0lxr
Mutation detailsThe lacZ and neomycin resistance genes containing gene trap vector inserted into intron 2 of the host gene. Transcrips from this allele will code for a fusion protein of the first 282 amino-acids of the host gene (which excludes the functional phosphatase domain), followed by beta-galactosidase and neo. Immunoblots show that a small amount of the wildtype L- and S-variants of the host gene peptides are still produced, possibly owing to splicing out of trap-containing intron 2. (J:243815)
Sequence Tags: 
Sequence tag details (1 tag)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ppm1b Mutation:  38 strains or lines available
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.13
The Jackson Laboratory