Del(2Hoxd11-Hoxd12)34Ddu
Targeted Allele Detail

Summary

• Symbol: Del(2Hoxd11-Hoxd12)34Ddu
• Name: deletion, Chr 2, Denis Duboule 34
• MGI ID: MGI:3776040
• Synonyms: Del34Ddu, HoxD^del(d12-11)
• Gene: Del(2Hoxd11-Hoxd12)34Ddu Location: Chr2:74505357-74517360 bp Genetic Position: Chr2, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:80090
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted
• Mutations: Intergenic deletion, Intragenic deletion
• Del(2Hoxd11-Hoxd12)34Ddu involves 3 genes/genome features (Hoxd12, Hoxd11, Hoxd10) View all
• Hoxd11 through 12 was deleted via trans-allelic meiotic recombination (TAMERE). (J:80090)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Del(2Hoxd11-Hoxd12)34Ddu Mutation: 1 strain or line available

References

• Original: J:80090 Kmita M, et al., Serial deletions and duplications suggest a mechanism for the collinearity of Hoxd genes in limbs. Nature. 2002 Nov 14;420(6912):145-50
• All: 2 reference(s)