Del(2Hoxd1-Hoxd10)26Ddu
Targeted Allele Detail
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Symbol: |
Del(2Hoxd1-Hoxd10)26Ddu |
Name: |
deletion, Chr 2, Denis Duboule 26 |
MGI ID: |
MGI:3689842 |
Synonyms: |
Del(1-10), Del1-10, Del26Ddu, HoxDDel(1-10) |
Gene: |
Del(2Hoxd1-Hoxd10)26Ddu Location: Chr2:74522268-74595486 bp Genetic Position: Chr2, Syntenic
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Germline Transmission: |
Earliest citation of germline transmission:
J:91567
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Parent Cell Line: |
D3 (ES Cell)
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Strain of Origin: |
129S2/SvPas
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Intergenic deletion, Intragenic deletion
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Del(2Hoxd1-Hoxd10)26Ddu involves 14 genes/genome features (Hoxd11, Hoxd10, Gm14396 ...)
View all
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Mutation details: Produced by targeted meiotic recombination in a cross between engineered loxP sites in the presence of Tg(Sycp1-cre)4Min. The entire the Hoxd1 through Hoxd10 genes are deleted. Hoxd11, Hoxd12 and Hoxd13 are brought into the vicinity of a possible early limb control region.
(J:91567)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Del(2Hoxd1-Hoxd10)26Ddu Mutation: |
0 strains or lines available
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Original: |
J:91567 Zakany J, et al., A dual role for Hox genes in limb anterior-posterior asymmetry. Science. 2004 Jun 11;304(5677):1669-72 |
All: |
6 reference(s) |
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