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KitW-bd
Spontaneous Allele Detail
Summary
Symbol: KitW-bd
Name: KIT proto-oncogene receptor tyrosine kinase; banded
MGI ID: MGI:1856258
Synonyms: W26H, Wbanded, Wbanded(bd)
Gene: Kit  Location: Chr5:75735647-75817382 bp, + strand  Genetic Position: Chr5, 39.55 cM
Alliance: KitW-bd page
Mutation
origin
Strain of Origin:  STOCK Rw Fgf5go Vps33abf
Mutation
description
Allele Type:    Spontaneous
Mutation:    Inversion
  KitW-bd involves 32 genes/genome features (Tec, Slain2, Slc10a4 ...) View all
 
Mutation detailsAnalysis using pulsed-field gel electrophoresis revealed that this allele comprises a 2.8 Mb inversion with one breakpoint 5' to the Kit coding sequence and the other breakpoint located between the genes Tec and Gabrb1. This inversion juxtaposes the genes Pdgfra and Gabrb1 on the proximal side and Kit and Tec on the distal side of the inversion. (J:38382)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Kit Mutation:  179 strains or lines available
References
Original:  J:13934 Beechey CV, et al., Two new W mutations. Mouse News Lett. 1983;68:70
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory