About   Help   FAQ
Dnajc2 Gene Detail
Summary
  • Symbol
    Dnajc2
  • Name
    DnaJ heat shock protein family (Hsp40) member C2
  • Synonyms
    Mida1, MIDA1, Zrf1, Zrf2
  • Feature Type
    protein coding gene
  • IDs
    MGI:99470
    NCBI Gene: 22791
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:21962279-21990183 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 9.97 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    894 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99470
 protein coding gene Chr5:21962265-21990249 (-)
129S1/SvImJ ENSMUSG00200009959
 protein coding gene Chr5:17599444-17627427 (-)
A/J ENSMUSG00195037402
 protein coding gene Chr5:17086322-17114518 (-)
AKR/J ENSMUSG00220033630
 protein coding gene Chr5:17120971-17149168 (-)
BALB/cJ ENSMUSG00180020552
 protein coding gene Chr5:16928474-16956460 (-)
C3H/HeJ ENSMUSG00175025963
 protein coding gene Chr5:18894562-18922757 (-)
C57BL/6NJ ENSMUSG00215014639
 protein coding gene Chr5:17495989-17523973 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026992
 protein coding gene Chr5:16752790-16782526 (-)
CAST/EiJ ENSTCUG00005003060
 protein coding gene Chr5:17163077-17190247 (-)
CBA/J ENSMUSG00210005146
 protein coding gene Chr5:17928743-17956938 (-)
DBA/2J ENSMUSG00185016399
 protein coding gene Chr5:19413532-19441048 (-)
FVB/NJ ENSMUSG00205024599
 protein coding gene Chr5:16627390-16655376 (-)
JF1/MsJ ENSUMUG00000004969
 protein coding gene Chr5:24020057-24047650 (-)
LP/J ENSMUSG00230022126
 protein coding gene Chr5:23881686-23909669 (-)
NOD/ShiLtJ ENSMUSG00190004112
 protein coding gene Chr5:16941675-16969189 (-)
NZO/HlLtJ ENSMUSG00225008661
 protein coding gene Chr5:29270121-29298326 (-)
PWK/PhJ ENSLUMG00010034566
 protein coding gene Chr5:17046316-17073481 (-)
SPRET/EiJ ENSMSPG00010029026
 protein coding gene Chr5:17943184-17973719 (-)
WSB/EiJ ENSIUOG00005031112
 protein coding gene Chr5:19750968-19778275 (-)



Homology
more
  • Human Ortholog
    DNAJC2, DnaJ heat shock protein family (Hsp40) member C2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DNAJC2, DnaJ heat shock protein family (Hsp40) member C2
  • Synonyms
    MPHOSPH11, MPP11, ZRF1, ZUO1
  • Links
    NCBI Gene ID: 27000
    UniProt: Q99543

  • Chr Location
    7q22.1; chr7:103312289-103344830 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 3 alleles in 3 genetic backgrounds
    23 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele die shortly after implantation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    42
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    670
  • Tissues
    53
  • cDNA Data
    14
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 22791 NCBI Gene Model | MGI Sequence Detail 27905 C57BL/6J ±  kb
    transcript NM_009584 RefSeq | MGI Sequence Detail 2053 ZRU/MplStud  
    polypeptide P54103 UniProt | EBI | MGI Sequence Detail 621 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      Genomic 1
      cDNA 15
      Primer pair 3
      Antibodies 1

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGD-MRK-16243, MGD-MRK-35113, MGI:106655, MGI:2141052
    References
    more
    • Summaries
      All 61
      Developmental Gene Expression 5
      Diseases 1
      Gene Ontology 9
      Phenotypes 23
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory