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Raly Gene Detail
Summary
  • Symbol
    Raly
  • Name
    hnRNP-associated with lethal yellow
  • Synonyms
    Merc
  • Feature Type
    protein coding gene
  • IDs
    MGI:97850
    NCBI Gene: 19383
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:154633016-154709181 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 76.83 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1303 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    4
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97850
 protein coding gene Chr2:154632989-154712930 (+)
129S1/SvImJ ENSMUSG00200027284
 protein coding gene Chr2:151497954-151573074 (+)
A/J ENSMUSG00195020329
 protein coding gene Chr2:151860962-151937132 (+)
AKR/J ENSMUSG00220043578
 protein coding gene Chr2:151150461-151226633 (+)
BALB/cJ ENSMUSG00180038512
 protein coding gene Chr2:151326098-151402220 (+)
C3H/HeJ ENSMUSG00175038163
 protein coding gene Chr2:152070230-152146357 (+)
C57BL/6NJ ENSMUSG00215025922
 protein coding gene Chr2:151480750-151556914 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024519
 protein coding gene Chr2:146728777-146805337 (+)
CAST/EiJ ENSTCUG00005041506
 protein coding gene Chr2:150481061-150557355 (+)
CBA/J ENSMUSG00210036082
 protein coding gene Chr2:152006737-152082868 (+)
DBA/2J ENSMUSG00185046077
 protein coding gene Chr2:151694059-151770247 (+)
FVB/NJ ENSMUSG00205034316
 protein coding gene Chr2:150773028-150849182 (+)
JF1/MsJ ENSUMUG00000022070
 protein coding gene Chr2:151349963-151426130 (+)
LP/J ENSMUSG00230033253
 protein coding gene Chr2:153295592-153376403 (+)
NOD/ShiLtJ ENSMUSG00190036793
 protein coding gene Chr2:151395661-151471780 (+)
NZO/HlLtJ ENSMUSG00225004375
 protein coding gene Chr2:161330670-161411504 (+)
PWK/PhJ ENSLUMG00010035087
 protein coding gene Chr2:151293834-151368646 (+)
SPRET/EiJ ENSMSPG00010028329
 protein coding gene Chr2:154108669-154183026 (+)
WSB/EiJ ENSIUOG00005042026
 protein coding gene Chr2:151093163-151168198 (+)



Homology
more
  • Human Ortholog
    RALY, RALY heterogeneous nuclear ribonucleoprotein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RALY, RALY heterogeneous nuclear ribonucleoprotein
  • Synonyms
    HNRPCL2, P542
  • Links
    NCBI Gene ID: 22913
    UniProt: Q9UKM9

  • Chr Location
    20q11.22; chr20:33993632-34108308 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 2 alleles in 3 genetic backgrounds
    44 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele are viable.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    639
  • Tissues
    30
  • cDNA Data
    15
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027593 Ensembl Gene Model | MGI Sequence Detail 76166 C57BL/6J ±  kb
    transcript ENSMUST00000029120 Ensembl | MGI Sequence Detail 1802 Not Applicable  
    polypeptide ENSMUSP00000029120 Ensembl | MGI Sequence Detail 312 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 30
      Genomic 8
      cDNA 18
      Primer pair 4
      Antibodies 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-13758, MGI:2139040
    References
    more
    • Summaries
      All 78
      Developmental Gene Expression 4
      Gene Ontology 8
      Phenotypes 44
    • Earliest
      J:12911 Michaud EJ, et al., The embryonic lethality of homozygous lethal yellow mice (Ay/Ay) is associated with the disruption of a novel RNA-binding protein. Genes Dev. 1993 Jul;7(7A):1203-13
    • Latest
      J:363261 He T, et al., Endothelial PD-1 Regulates Vascular Homeostasis and Oligodendrogenesis during Brain Development. Adv Sci (Weinh). 2025 Feb 27;:e2417410
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory