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Nedd1 Gene Detail
Summary
  • Symbol
    Nedd1
  • Name
    neural precursor cell expressed, developmentally down-regulated gene 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:97293
    NCBI Gene: 17997
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:92520608-92558282 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 47.25 cM, cytoband C2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    938 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97293
 protein coding gene Chr10:92520607-92559544 (-)
129S1/SvImJ ENSMUSG00200029606
 protein coding gene Chr10:89032684-89070419 (-)
A/J ENSMUSG00195020989
 protein coding gene Chr10:89477499-89515239 (-)
AKR/J ENSMUSG00220021451
 protein coding gene Chr10:89045050-89082790 (-)
BALB/cJ ENSMUSG00180029533
 protein coding gene Chr10:89480273-89518016 (-)
C3H/HeJ ENSMUSG00175021360
 protein coding gene Chr10:89376276-89414020 (-)
C57BL/6NJ ENSMUSG00215025297
 protein coding gene Chr10:89032613-89070289 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015727
 protein coding gene Chr10:86430246-86470219 (-)
CAST/EiJ ENSTCUG00005029967
 protein coding gene Chr10:88767856-88805612 (-)
CBA/J ENSMUSG00210031308
 protein coding gene Chr10:89216280-89254025 (-)
DBA/2J ENSMUSG00185040778
 protein coding gene Chr10:89427926-89465666 (-)
FVB/NJ ENSMUSG00205011446
 protein coding gene Chr10:89131885-89169627 (-)
JF1/MsJ ENSUMUG00000021542
 protein coding gene Chr10:90828667-90866356 (-)
LP/J ENSMUSG00230018399
 protein coding gene Chr10:91328065-91366117 (-)
NOD/ShiLtJ ENSMUSG00190017895
 protein coding gene Chr10:89462099-89499839 (-)
NZO/HlLtJ ENSMUSG00225021346
 protein coding gene Chr10:95592665-95630746 (-)
PWK/PhJ ENSLUMG00010020991
 protein coding gene Chr10:89101475-89139112 (-)
SPRET/EiJ ENSMSPG00010031403
 protein coding gene Chr10:90724355-90762244 (-)
WSB/EiJ ENSIUOG00005034835
 protein coding gene Chr10:89162850-89200592 (-)



Homology
more
  • Human Ortholog
    NEDD1, NEDD1 gamma-tubulin ring complex targeting factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NEDD1, NEDD1 gamma-tubulin ring complex targeting factor
  • Synonyms
    GCP-WD, TUBGCP7
  • Links
    NCBI Gene ID: 121441
    UniProt: Q8NHV4

  • Chr Location
    12q23.1; chr12:96907224-96953780 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    667
  • Tissues
    35
  • cDNA Data
    104
  • Literature Summary
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000019988 Ensembl Gene Model | MGI Sequence Detail 37675 C57BL/6J ±  kb
    transcript ENSMUST00000020163 Ensembl | MGI Sequence Detail 3534 Not Applicable  
    polypeptide ENSMUSP00000020163 Ensembl | MGI Sequence Detail 660 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 104
      cDNA 104
      Antibodies 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-12806
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 9
      Gene Ontology 7
      Phenotypes 14
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory