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H2-M5 Gene Detail
Summary
  • Symbol
    H2-M5
  • Name
    histocompatibility 2, M region locus 5
  • Synonyms
    CRW2, D130003B22Rik, H-2M5
  • Feature Type
    protein coding gene
  • IDs
    MGI:95917
    NCBI Gene: 240095
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:37294953-37300429 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 19.16 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95917
 protein coding gene Chr17:37294677-37308847 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023692
 protein coding gene Chr17:37344965-37350190 (-)
A/J MGP_AJ_G0023650
 protein coding gene Chr17:36165716-36171164 (-)
AKR/J MGP_AKRJ_G0023621
 protein coding gene Chr17:36599764-36607044 (-)
BALB/cJ MGP_BALBcJ_G0023657
 protein coding gene Chr17:36409805-36415290 (-)
C3H/HeJ MGP_C3HHeJ_G0023419
 protein coding gene Chr17:37116030-37122625 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024095
 protein coding gene Chr17:38941380-38946598 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021563
 protein coding gene Chr17:33979350-33984765 (-)
CAST/EiJ MGP_CASTEiJ_G0022904
 protein coding gene Chr17:37246729-37251927 (-)
CBA/J MGP_CBAJ_G0023396
 protein coding gene Chr17:40459363-40464790 (-)
DBA/2J MGP_DBA2J_G0023521
 protein coding gene Chr17:35557123-35562331 (-)
FVB/NJ MGP_FVBNJ_G0023494
 protein coding gene Chr17:35164639-35170254 (-)
LP/J MGP_LPJ_G0023599
 protein coding gene Chr17:37871666-37879326 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023517
 protein coding gene Chr17:39248553-39255309 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024140
 protein coding gene Chr17:36945717-36951181 (-)
PWK/PhJ MGP_PWKPhJ_G0022656
 protein coding gene Chr17:34337698-34343418 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022475
 protein coding gene Chr17:35027929-35039988 (-)
WSB/EiJ MGP_WSBEiJ_G0022971
 protein coding gene Chr17:37261495-37266729 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    3
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000024459 Ensembl Gene Model | MGI Sequence Detail 5477 C57BL/6J ±  kb
    transcript ENSMUST00000169189 Ensembl | MGI Sequence Detail 1170 Not Applicable  
    polypeptide ENSMUSP00000131365 Ensembl | MGI Sequence Detail 348 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • InterPro Domains
      IPR050208 Antigen-presenting and immune regulatory MHC class I-related
      IPR003597 Immunoglobulin C1-set
      IPR007110 Immunoglobulin-like domain
      IPR036179 Immunoglobulin-like domain superfamily
      IPR013783 Immunoglobulin-like fold
      IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
      IPR011162 MHC classes I/II-like antigen recognition protein
      IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
      IPR011161 MHC class I-like antigen recognition-like
      IPR037055 MHC class I-like antigen recognition-like superfamily
    Molecular
    Reagents
    less
    • All nucleic 16
      Genomic 10
      cDNA 3
      Primer pair 1
      Other 2

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGD-MRK-10402, MGD-MRK-10513, MGI:3036265
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 1
      Phenotypes 14
    • Earliest
      J:13181 Wang CR, et al., Organization and structure of the H-2M4-M8 class I genes in the mouse major histocompatibility complex. Immunogenetics. 1993;38(4):258-71
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    06/09/2026
    MGI 6.24     		The Jackson Laboratory