About   Help   FAQ
Tmem165 Gene Detail
Summary
  • Symbol
    Tmem165
  • Name
    transmembrane protein 165
  • Synonyms
    pFT27, Tpardl, Tparl
  • Feature Type
    protein coding gene
  • IDs
    MGI:894407
    NCBI Gene: 21982
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:76331727-76357091 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 40.56 cM
  • Mapping Data
    6 experiments
Strain
Comparison
more
  • SNPs within 2kb
    647 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_894407
 protein coding gene Chr5:76331727-76357092 (+)
129S1/SvImJ ENSMUSG00200000872
 protein coding gene Chr5:72022151-72047520 (+)
A/J ENSMUSG00195010304
 protein coding gene Chr5:71318923-71344294 (+)
AKR/J ENSMUSG00220014695
 protein coding gene Chr5:71432090-71457460 (+)
BALB/cJ ENSMUSG00180022975
 protein coding gene Chr5:71093616-71118981 (+)
C3H/HeJ ENSMUSG00175004207
 protein coding gene Chr5:73137435-73162822 (+)
C57BL/6NJ ENSMUSG00215000437
 protein coding gene Chr5:71908199-71933565 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027313
 protein coding gene Chr5:69096227-69124539 (+)
CAST/EiJ ENSTCUG00005013585
 protein coding gene Chr5:70882644-70909319 (+)
CBA/J ENSMUSG00210000438
 protein coding gene Chr5:72075430-72100813 (+)
DBA/2J ENSMUSG00185016293
 protein coding gene Chr5:73905375-73930759 (+)
FVB/NJ ENSMUSG00205017719
 protein coding gene Chr5:70841941-70867314 (+)
JF1/MsJ ENSUMUG00000004728
 protein coding gene Chr5:78387215-78412645 (+)
LP/J ENSMUSG00230020989
 protein coding gene Chr5:78596150-78621519 (+)
NOD/ShiLtJ ENSMUSG00190007674
 protein coding gene Chr5:71025765-71051136 (+)
NZO/HlLtJ ENSMUSG00225033009
 protein coding gene Chr5:83642869-83668234 (+)
PWK/PhJ ENSLUMG00010007256
 protein coding gene Chr5:70979330-71004973 (+)
SPRET/EiJ ENSMSPG00010008876
 protein coding gene Chr5:72969917-72996670 (+)
WSB/EiJ ENSIUOG00005017998
 protein coding gene Chr5:73855341-73880723 (+)



Homology
more
  • Human Ortholog
    TMEM165, transmembrane protein 165
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM165, transmembrane protein 165
  • Synonyms
    CDG2K, FT27, GDT1, SLC64A1, TMPT27, TPARL
  • Links
    NCBI Gene ID: 55858
    UniProt: Q9HC07

  • Chr Location
    4q12; chr4:55395652-55453397 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human TMEM165 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    35
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    123
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 21982 NCBI Gene Model | MGI Sequence Detail 25365 C57BL/6J ±  kb
    transcript NM_011626 RefSeq | MGI Sequence Detail 1896 C57BL/6  
    polypeptide P52875 UniProt | EBI | MGI Sequence Detail 323 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 127
      Genomic 4
      cDNA 123

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2141106
    References
    more
    • Summaries
      All 50
      Gene Ontology 8
      Phenotypes 17
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory