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C1qb Gene Detail
Summary
  • Symbol
    C1qb
  • Name
    complement component 1, q subcomponent, beta polypeptide
  • Feature Type
    protein coding gene
  • IDs
    MGI:88224
    NCBI Gene: 12260
  • Alliance
    genome feature page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:136607440-136613498 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 69.05 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    260 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88224
 protein coding gene Chr4:136607437-136613511 (-)
129S1/SvImJ ENSMUSG00200018814
 protein coding gene Chr4:130025145-130031203 (-)
A/J ENSMUSG00195043401
 protein coding gene Chr4:131379347-131385465 (-)
AKR/J ENSMUSG00220040855
 protein coding gene Chr4:130371108-130377226 (-)
BALB/cJ ENSMUSG00180046575
 protein coding gene Chr4:129015522-129021648 (-)
C3H/HeJ ENSMUSG00175031831
 protein coding gene Chr4:130036965-130043075 (-)
C57BL/6NJ ENSMUSG00215050172
 protein coding gene Chr4:131547967-131554025 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026668
 protein coding gene Chr4:126564918-126571141 (-)
CAST/EiJ ENSTCUG00005046546
 protein coding gene Chr4:130956374-130962409 (-)
CBA/J ENSMUSG00210052915
 protein coding gene Chr4:129660888-129666998 (-)
DBA/2J ENSMUSG00185051704
 protein coding gene Chr4:131188824-131194950 (-)
FVB/NJ ENSMUSG00205041492
 protein coding gene Chr4:129429315-129435440 (-)
JF1/MsJ ENSUMUG00000019331
 protein coding gene Chr4:131881981-131888039 (-)
LP/J ENSMUSG00230040170
 protein coding gene Chr4:134963326-134969384 (-)
NOD/ShiLtJ ENSMUSG00190042672
 protein coding gene Chr4:129420836-129426962 (-)
NZO/HlLtJ ENSMUSG00225026610
 protein coding gene Chr4:140918404-140924462 (-)
PWK/PhJ ENSLUMG00010044947
 protein coding gene Chr4:128869022-128875140 (-)
SPRET/EiJ ENSMSPG00010038480
 protein coding gene Chr4:130937225-130943274 (-)
WSB/EiJ ENSIUOG00005035148
 protein coding gene Chr4:129316862-129322980 (-)



Homology
more
  • Human Ortholog
    C1QB, complement C1q B chain
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C1QB, complement C1q B chain
  • Synonyms
    C1QD2
  • Links
    NCBI Gene ID: 713
    UniProt: P02746

  • Chr Location
    1p36.12; chr1:22652713-22661637 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    13
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    6
  • Targeted
    5
  • Genomic Mutations
    3 involving C1qb
  • Find Mice (IMSR)
    13 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    36
  • GO References
    14
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    643
  • Tissues
    32
  • cDNA Data
    123
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036905 Ensembl Gene Model | MGI Sequence Detail 6059 C57BL/6J ±  kb
transcript ENSMUST00000046384 Ensembl | MGI Sequence Detail 1088 Not Applicable  
polypeptide ENSMUSP00000040246 Ensembl | MGI Sequence Detail 253 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 127
    Genomic 3
    cDNA 124

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-1697
References
more
  • Summaries
    All 62
    Developmental Gene Expression 6
    Gene Ontology 14
    Phenotypes 11
  • Earliest
    J:10130 Petry F, et al., Molecular cloning and characterization of the complementary DNA coding for the B-chain of murine Clq. FEBS Lett. 1989 Nov 20;258(1):89-93
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory