About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:253351 Hanley O, et al., Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns. Neuron. 2016 Sep 7;91(5):1005-1020
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8209239
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen S1H Control left: embryonic day 12.5 (more )
Note: Control animals are from age-matched littermates that are Cre-negative and either Pbx3+/+ or Pbx3+/-. Triple labeled: green - Casp3; red - Isl1 (assay MGI:8206395) and Isl2 (assay MGI:8207778); blue - Mnx1 (assay MGI:8207842).
Structure Cell Type Level Pattern Image Note
TS20: spinal cord spinal cord motor neuron Present Single cells S1H Control left Expression was in apoptotic cells.
Specimen S1H PbxMNdelta left: embryonic day 12.5; Olig2tm1(cre)Tmj/Olig2+, Pbx1tm1Koss/Pbx1tm1Koss, Pbx3tm1Mlc/Pbx3tm1Mlc (more )
Note: Conditional mutant. Triple labeled: green - Casp3; red - Isl1 (assay MGI:8206395) and Isl2 (assay MGI:8207778); blue - Mnx1 (assay MGI:8207842).
Structure Cell Type Level Pattern Image Note
TS20: spinal cord spinal cord motor neuron Present Single cells S1H PbxMNdelta left Expression was in apoptotic cells.
Specimen S1H Control right: embryonic day 12.5 (more )
Note: Control animals are from age-matched littermates that are Cre-negative and either Pbx3+/+ or Pbx3+/-. Triple labeled: green - Casp3; red - Isl1 (assay MGI:8206395) and Isl2 (assay MGI:8207778); blue - Mnx1 (assay MGI:8207842).
Structure Cell Type Level Pattern Image Note
TS20: spinal cord spinal cord motor neuron Present Single cells S1H Control right Expression was in apoptotic cells.
Specimen S1H PbxMNdelta right: embryonic day 12.5; Olig2tm1(cre)Tmj/Olig2+, Pbx1tm1Koss/Pbx1tm1Koss, Pbx3tm1Mlc/Pbx3tm1Mlc (more )
Note: Conditional mutant. Triple labeled: green - Casp3; red - Isl1 (assay MGI:8206395) and Isl2 (assay MGI:8207778); blue - Mnx1 (assay MGI:8207842).
Structure Cell Type Level Pattern Image Note
TS20: spinal cord spinal cord motor neuron Present Single cells S1H PbxMNdelta right Expression was in apoptotic cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory