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Gene Expression Data
Assay Details
Assay
Reference: J:253351 Hanley O, et al., Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns. Neuron. 2016 Sep 7;91(5):1005-1020
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8207835
Gene symbol: Sox5
Gene name: SRY (sex determining region Y)-box 5
Antibody: Anti-Sox5
Results
Specimen 2M Control: embryonic day 12.5 (more )
Note: Control animals are from age-matched littermates that are Cre-negative and either Pbx3+/+ or Pbx3+/-.
Structure Cell Type Level Pattern Image Note
TS20: spinal cord brachial region spinal cord motor neuron Present Regionally restricted 2M Control Expression was detected in non-lateral motor column neurons.
Specimen 2M PbxMNdelta: embryonic day 12.5; Olig2tm1(cre)Tmj/Olig2+, Pbx1tm1Koss/Pbx1tm1Koss, Pbx3tm1Mlc/Pbx3tm1Mlc (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS20: spinal cord brachial region spinal cord motor neuron Absent 2M PbxMNdelta Expression was lost in non-lateral motor column neurons.
Specimen S7B left: embryonic day 12.5 (more )
Note: Rostral cervical level section. Double labeled: red - Sox5; green - Mecom (assay MGI:8209108).
Structure Cell Type Level Pattern Image Note
TS20: spinal cord cervical region spinal cord motor neuron Present Regionally restricted S7B left Expression did not overlap with Mecom immunostaining.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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