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Gene Expression Data
Assay Details
Assay
Reference: J:306107 Niborski LL, et al., Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model. Dis Model Mech. 2021 May 1;14(5):dmm047498
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8187726
Gene symbol: Vil1
Gene name: villin 1
Antibody: anti-VIL1
Assay notes: Embryos and postnatal kidneys up to 2 months of age were fixed with 60% ethanol/11% formaldehyde and 10% acetic acid.
Results
Specimen 5A: embryonic day 15.5 (more )
Note: Double labeled: red - Vil1; green - Hnf4a (assay MGI:8187725).
Structure Level Pattern Image Note
TS23: cortical early proximal tubule Present Regionally restricted 5A Expression localized at proximal tubule brush border.

Specimen 5B/C: embryonic day 15.5; Hnf1btm2.1Sce/Hnf1b+ (more )
Note: Double labeled: red - Vil1; green - Hnf4a (assay MGI:8187725).
Structure Level Pattern Image Note
TS23: cortical early proximal tubule Present Regionally restricted 5C , 5B Expression at proximal tubule brush border interrupted in several regions of cystic structures..

Specimen 5D: embryonic day 15.5 (more )
Note: Double labeled: red - Vil1; green - Hnf1b (assay MGI:8187721).
Structure Level Pattern Image Note
TS23: cortical early proximal tubule Present Regionally restricted 5D Expression localized at proximal tubule brush border.

Specimen 5E/F: embryonic day 15.5; Hnf1btm2.1Sce/Hnf1b+ (more )
Note: Double labeled: red - Vil1; green - Hnf1b (assay MGI:8187721).
Structure Level Pattern Image Note
TS23: cortical early proximal tubule Present Regionally restricted 5E , 5F Expression at proximal tubule brush border interrupted in several regions of cystic structures..


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory