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Gene Expression Data
Assay Details
Assay
Reference: J:182740 Moya IM, et al., Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades. Dev Cell. 2012 Mar 13;22(3):501-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8187625
Gene symbol: Golga2
Gene name: golgin A2
Antibody: anti-GM130 Clone 35/GM130 (#610822)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 2G Ctrl: embryonic day 9.5; Smad1tm2Rob/Smad1+, Smad5tm1Huy/Smad5+ (more )
Note: Double labeled: red - Golga2; green - Pecam1 (assay MGI:8187623).
Structure Cell Type Level Pattern Image Note
TS15: head blood vessel endothelial tip cell Present 2G Ctrl Tip cells were polarized with a compacted Golgi apparatus facing the leading edge of the cell.
Specimen 2G dKO: embryonic day 9.5; Smad1tm2Rob/Smad1tm2Rob, Smad5tm1Huy/Smad5tm1Huy, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant. Double labeled: red - Golga2; green - Pecam1 (assay MGI:8187623).
Structure Level Pattern Image Note
TS15: head blood vessel Present 2G dKO The localization and compaction of the Golgi apparatus in tip-like cells of mutant embryos was random.
Specimen S3A Ctrl left: embryonic day 9.5; Smad1tm2Rob/Smad1+, Smad5tm1Huy/Smad5+ (more )
Note: Double labeled: red - Golga2; green - Pecam1 (assay MGI:8187623).
Structure Cell Type Level Pattern Image Note
TS15: head blood vessel endothelial tip cell Present S3A Ctrl left , S3A Ctrl left enlarged Tip cells were polarized with a compacted Golgi apparatus facing the leading edge of the cell.
Specimen S3A Ctrl right: embryonic day 9.5; Smad1tm2Rob/Smad1+, Smad5tm1Huy/Smad5+ (more )
Note: Double labeled: red - Golga2; green - Pecam1 (assay MGI:8187623).
Structure Cell Type Level Pattern Image Note
TS15: head blood vessel endothelial tip cell Present S3A Ctrl right enlarged , S3A Ctrl right Tip cells were polarized with a compacted Golgi apparatus facing the leading edge of the cell.
Specimen S3A dKO left: embryonic day 9.5; Smad1tm2Rob/Smad1tm2Rob, Smad5tm1Huy/Smad5tm1Huy, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant. Double labeled: red - Golga2; green - Pecam1 (assay MGI:8187623).
Structure Cell Type Level Pattern Image Note
TS15: head blood vessel blood vessel endothelial cell Present S3A dKO-1 , S3A dKO-2 The localization and compaction of the Golgi apparatus in tip-like cells of mutant embryos was random.
Specimen S3A dKO middle: embryonic day 9.5; Smad1tm2Rob/Smad1tm2Rob, Smad5tm1Huy/Smad5tm1Huy, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant. Double labeled: red - Golga2; green - Pecam1 (assay MGI:8187623).
Structure Cell Type Level Pattern Image Note
TS15: head blood vessel blood vessel endothelial cell Present S3A dKO-3 , S3A dKO-4 The localization and compaction of the Golgi apparatus in tip-like cells of mutant embryos was random.
Specimen S3A dKO right: embryonic day 9.5; Smad1tm2Rob/Smad1tm2Rob, Smad5tm1Huy/Smad5tm1Huy, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant. Double labeled: red - Golga2; green - Pecam1 (assay MGI:8187623).
Structure Cell Type Level Pattern Image Note
TS15: head blood vessel blood vessel endothelial cell Present S3A dKO-5 , S3A dKO-7 , S3A dKO-6 The localization and compaction of the Golgi apparatus in tip-like cells of mutant embryos was random.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory